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PD-1 Interaction with PD-L1 but not PD-L2 on B-cells Mediates Protective Effects of Estrogen against EAE

Increased remissions in multiple sclerosis (MS) during late pregnancy may result from high levels of sex steroids such as estrogen and estriol. Estrogen (E2=17β-estradiol) protects against experimental autoimmune encephalomyelitis (EAE), but the cellular basis for E2-induced protection remains uncle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bodhankar, Sheetal, Galipeau, Danielle, Vandenbark, Arthur A, Offner, Halina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760596/
https://ncbi.nlm.nih.gov/pubmed/24009988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000143
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