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PD-1 Interaction with PD-L1 but not PD-L2 on B-cells Mediates Protective Effects of Estrogen against EAE

Increased remissions in multiple sclerosis (MS) during late pregnancy may result from high levels of sex steroids such as estrogen and estriol. Estrogen (E2=17β-estradiol) protects against experimental autoimmune encephalomyelitis (EAE), but the cellular basis for E2-induced protection remains uncle...

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Bibliografiska uppgifter
Huvudupphovsmän: Bodhankar, Sheetal, Galipeau, Danielle, Vandenbark, Arthur A, Offner, Halina
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760596/
https://ncbi.nlm.nih.gov/pubmed/24009988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000143
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