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PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1
BACKGROUND: Stroke severity is worsened by recruitment of inflammatory immune cells into the brain. This process depends in part on T cell activation, in which the B7 family of co-stimulatory molecules plays a pivotal role. Previous studies demonstrated more severe infarcts in mice lacking programme...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846120/ https://ncbi.nlm.nih.gov/pubmed/24015822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-111 |
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