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PD-L1 mAb Treats Ischemic Stroke by Controlling CNS Inflammation
BACKGROUND AND PURPOSE: Both pathogenic and regulatory immune processes are involved in the middle cerebral artery occlusion (MCAO) model of experimental stroke, including interactions involving the Programmed Death 1 (PD-1) receptor and its two ligands, PD-L1 and PD-L2. Although PD-1 reduced stroke...
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| Udgivet i: | Stroke |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589506/ https://ncbi.nlm.nih.gov/pubmed/26306753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.010592 |
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