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Autoimmune susceptibility imposed by public TCRβ chains

Although the TCR repertoire is highly diverse, a small fraction of TCR chains, referred to as public, preferentially form and are shared by most individuals. Prior studies indicated that public TCRβ may be preferentially deployed in autoimmunity. We hypothesized that if these TCRβ modulate the likel...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Zhao, Yunqian, Nguyen, Phuong, Vogel, Peter, Li, Bofeng, Jones, Lindsay L., Geiger, Terrence L.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116635/
https://ncbi.nlm.nih.gov/pubmed/27869234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37543
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