Загрузка...
Altered differentiation, diminished pathogenicity, and regulatory activity of myelin-specific T cells expressing an enhanced affinity TCR
Whereas increased affinity enhances T cell competitiveness after immunization, the role of affinity in modulating the pathogenicity of self-reactive T cells is less established. To assess this, we generated two myelin-specific, class II MHC-restricted TCR that differ only in a buried hydroxymethyl t...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221875/ https://ncbi.nlm.nih.gov/pubmed/22025553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102202 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|