Subtle affinity-enhancing mutations in a MOG-specific TCR alter specificity and generate new self-reactivity

समान संसाधन

• Altered differentiation, diminished pathogenicity, and regulatory activity of myelin-specific T cells expressing an enhanced affinity TCR
  द्वारा: Alli, Rajshekhar, और अन्य
  प्रकाशित: (2011)
• Retrogenic modeling of experimental allergic encephalomyelitis associates T-cell frequency but not T-cell receptor functional affinity with pathogenicity
  द्वारा: Alli, Rajshekhar, और अन्य
  प्रकाशित: (2008)
• Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy
  द्वारा: Udyavar, Akshata, और अन्य
  प्रकाशित: (2010)
• Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3(+) regulatory T lymphocytes in MOG-EAE
  द्वारा: Nguyen, Phuong, और अन्य
  प्रकाशित: (2010)
• The T cell response to interleukin 10 alters cellular dynamics and paradoxically promotes CNS autoimmunity
  द्वारा: Liu, Xin, और अन्य
  प्रकाशित: (2012)