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IL-6 promotes T cell proliferation and expansion under inflammatory conditions in association with low-level RORγt expression

IL-6 is a critical driver of acute and chronic inflammation, and has been reported to act as a T cell survival factor. The influence of IL-6 on T cell homeostasis is not well resolved. We demonstrate that IL-6 signaling drives T cell expansion under inflammatory conditions, but not during normal hom...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Li, Bofeng, Jones, Lindsay L., Geiger, Terrence L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324200/
https://ncbi.nlm.nih.gov/pubmed/30315140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800016
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