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IL-6 promotes T cell proliferation and expansion under inflammatory conditions in association with low-level RORγt expression
IL-6 is a critical driver of acute and chronic inflammation, and has been reported to act as a T cell survival factor. The influence of IL-6 on T cell homeostasis is not well resolved. We demonstrate that IL-6 signaling drives T cell expansion under inflammatory conditions, but not during normal hom...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324200/ https://ncbi.nlm.nih.gov/pubmed/30315140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800016 |
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