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IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease
The ability of CD4+ T cells to change their phenotype and to specialize into different functional subsets may enhance the risk of autoimmune diseases. Here we investigate how a pleiotropic cytokine interleukin (IL)-15 may modify the functional commitment of CD4+ T cells expressing the lineage-associ...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792960/ https://ncbi.nlm.nih.gov/pubmed/26964669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10888 |
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