Defined microbiota transplant restores Th17/RORγt(+) regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

The building evidence for the contribution of microbiota to human disease has spurred an effort to develop therapies that target the gut microbiota. This is particularly evident in inflammatory bowel diseases (IBDs), where clinical trials of fecal microbiota transplantation have shown some efficacy....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Britton, Graham J., Contijoch, Eduardo J., Spindler, Matthew P., Aggarwala, Varun, Dogan, Belgin, Bongers, Gerold, San Mateo, Lani, Baltus, Andrew, Das, Anuk, Gevers, Dirk, Borody, Thomas J., Kaakoush, Nadeem O., Kamm, Michael A., Mitchell, Hazel, Paramsothy, Sudarshan, Clemente, Jose C., Colombel, Jean-Frederic, Simpson, Kenneth W., Dubinsky, Marla C., Grinspan, Ari, Faith, Jeremiah J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474624/
https://ncbi.nlm.nih.gov/pubmed/32817490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922189117
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