Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt(+) Regulatory T Cells and Exacerbate Colitis in Mice

Microbiota are thought to influence the development and progression of inflammatory bowel disease (IBD), but determining generalizable effects of microbiota on IBD etiology requires larger-scale functional analyses. We colonized germ-free mice with intestinal microbiotas from 30 healthy and IBD dono...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Immunity
Prif Awduron: Britton, Graham J., Contijoch, Eduardo J., Mogno, Ilaria, Vennaro, Olivia H., Llewellyn, Sean R., Ng, Ruby, Li, Zhihua, Mortha, Arthur, Merad, Miriam, Das, Anuk, Gevers, Dirk, McGovern, Dermot P.B., Singh, Namita, Braun, Jonathan, Jacobs, Jonathan P., Clemente, Jose C., Grinspan, Ari, Sands, Bruce E., Colombel, Jean-Frederic, Dubinsky, Marla C., Faith, Jeremiah J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512335/
https://ncbi.nlm.nih.gov/pubmed/30650377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.12.015
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg