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Autoimmune susceptibility imposed by public TCRβ chains

Although the TCR repertoire is highly diverse, a small fraction of TCR chains, referred to as public, preferentially form and are shared by most individuals. Prior studies indicated that public TCRβ may be preferentially deployed in autoimmunity. We hypothesized that if these TCRβ modulate the likel...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Zhao, Yunqian, Nguyen, Phuong, Vogel, Peter, Li, Bofeng, Jones, Lindsay L., Geiger, Terrence L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116635/
https://ncbi.nlm.nih.gov/pubmed/27869234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37543
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