Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Anti-bone resorptive drugs such as bisphosphonates, the anti-RANKL antibody (denosumab), or selective estrogen receptor modulators (SERMs) have been developed to treat osteoporosis. Mechanisms underlying activity of bisphosphonates or denosumab in this context are understood, while it is less clear...

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Udgivet i:PLoS One
Main Authors: Morita, Mayu, Sato, Yuiko, Iwasaki, Ryotaro, Kobayashi, Tami, Watanabe, Ryuichi, Oike, Takatsugu, Miyamoto, Kana, Toyama, Yoshiaki, Matsumoto, Morio, Nakamura, Masaya, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089792/
https://ncbi.nlm.nih.gov/pubmed/27802325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165922
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