Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Anti-bone resorptive drugs such as bisphosphonates, the anti-RANKL antibody (denosumab), or selective estrogen receptor modulators (SERMs) have been developed to treat osteoporosis. Mechanisms underlying activity of bisphosphonates or denosumab in this context are understood, while it is less clear...

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Publicat a:PLoS One
Autors principals: Morita, Mayu, Sato, Yuiko, Iwasaki, Ryotaro, Kobayashi, Tami, Watanabe, Ryuichi, Oike, Takatsugu, Miyamoto, Kana, Toyama, Yoshiaki, Matsumoto, Morio, Nakamura, Masaya, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089792/
https://ncbi.nlm.nih.gov/pubmed/27802325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165922
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