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Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Anti-bone resorptive drugs such as bisphosphonates, the anti-RANKL antibody (denosumab), or selective estrogen receptor modulators (SERMs) have been developed to treat osteoporosis. Mechanisms underlying activity of bisphosphonates or denosumab in this context are understood, while it is less clear...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Morita, Mayu, Sato, Yuiko, Iwasaki, Ryotaro, Kobayashi, Tami, Watanabe, Ryuichi, Oike, Takatsugu, Miyamoto, Kana, Toyama, Yoshiaki, Matsumoto, Morio, Nakamura, Masaya, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089792/
https://ncbi.nlm.nih.gov/pubmed/27802325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165922
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