HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis

In women, estrogen deficiency after menopause frequently accelerates osteoclastic bone resorption, leading to osteoporosis, the most common skeletal disorder. However, mechanisms underlying osteoporosis resulting from estrogen deficiency remain largely unknown. Here we show that in bone-resorbing os...

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Detalhes bibliográficos
Main Authors: Miyauchi, Yoshiteru, Sato, Yuiko, Kobayashi, Tami, Yoshida, Shigeyuki, Mori, Tomoaki, Kanagawa, Hiroya, Katsuyama, Eri, Fujie, Atsuhiro, Hao, Wu, Miyamoto, Kana, Tando, Toshimi, Morioka, Hideo, Matsumoto, Morio, Chambon, Pierre, Johnson, Randall S., Kato, Shigeaki, Toyama, Yoshiaki, Miyamoto, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799362/
https://ncbi.nlm.nih.gov/pubmed/24023068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308755110
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