Interleukin-1 Receptor-associated Kinase-4 (IRAK4) Promotes Inflammatory Osteolysis by Activating Osteoclasts and Inhibiting Formation of Foreign Body Giant Cells

Formation of foreign body giant cells (FBGCs) occurs following implantation of medical devices such as artificial joints and is implicated in implant failure associated with inflammation or microbial infection. Two major macrophage subpopulations, M1 and M2, play different roles in inflammation and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Katsuyama, Eri, Miyamoto, Hiroya, Kobayashi, Tami, Sato, Yuiko, Hao, Wu, Kanagawa, Hiroya, Fujie, Atsuhiro, Tando, Toshimi, Watanabe, Ryuichi, Morita, Mayu, Miyamoto, Kana, Niki, Yasuo, Morioka, Hideo, Matsumoto, Morio, Toyama, Yoshiaki, Miyamoto, Takeshi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2015
विषय:
Cell Biology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294496/
https://ncbi.nlm.nih.gov/pubmed/25404736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568360
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