Interleukin-1 Receptor-associated Kinase-4 (IRAK4) Promotes Inflammatory Osteolysis by Activating Osteoclasts and Inhibiting Formation of Foreign Body Giant Cells

Formation of foreign body giant cells (FBGCs) occurs following implantation of medical devices such as artificial joints and is implicated in implant failure associated with inflammation or microbial infection. Two major macrophage subpopulations, M1 and M2, play different roles in inflammation and...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Katsuyama, Eri, Miyamoto, Hiroya, Kobayashi, Tami, Sato, Yuiko, Hao, Wu, Kanagawa, Hiroya, Fujie, Atsuhiro, Tando, Toshimi, Watanabe, Ryuichi, Morita, Mayu, Miyamoto, Kana, Niki, Yasuo, Morioka, Hideo, Matsumoto, Morio, Toyama, Yoshiaki, Miyamoto, Takeshi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294496/
https://ncbi.nlm.nih.gov/pubmed/25404736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568360
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