Interleukin-1 Receptor-associated Kinase-4 (IRAK4) Promotes Inflammatory Osteolysis by Activating Osteoclasts and Inhibiting Formation of Foreign Body Giant Cells

Formation of foreign body giant cells (FBGCs) occurs following implantation of medical devices such as artificial joints and is implicated in implant failure associated with inflammation or microbial infection. Two major macrophage subpopulations, M1 and M2, play different roles in inflammation and...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Katsuyama, Eri, Miyamoto, Hiroya, Kobayashi, Tami, Sato, Yuiko, Hao, Wu, Kanagawa, Hiroya, Fujie, Atsuhiro, Tando, Toshimi, Watanabe, Ryuichi, Morita, Mayu, Miyamoto, Kana, Niki, Yasuo, Morioka, Hideo, Matsumoto, Morio, Toyama, Yoshiaki, Miyamoto, Takeshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294496/
https://ncbi.nlm.nih.gov/pubmed/25404736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568360
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