HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis

In women, estrogen deficiency after menopause frequently accelerates osteoclastic bone resorption, leading to osteoporosis, the most common skeletal disorder. However, mechanisms underlying osteoporosis resulting from estrogen deficiency remain largely unknown. Here we show that in bone-resorbing os...

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Bibliografski detalji
Glavni autori: Miyauchi, Yoshiteru, Sato, Yuiko, Kobayashi, Tami, Yoshida, Shigeyuki, Mori, Tomoaki, Kanagawa, Hiroya, Katsuyama, Eri, Fujie, Atsuhiro, Hao, Wu, Miyamoto, Kana, Tando, Toshimi, Morioka, Hideo, Matsumoto, Morio, Chambon, Pierre, Johnson, Randall S., Kato, Shigeaki, Toyama, Yoshiaki, Miyamoto, Takeshi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799362/
https://ncbi.nlm.nih.gov/pubmed/24023068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308755110
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