Elevation of pro-inflammatory cytokine levels following anti-resorptive drug treatment is required for osteonecrosis development in infectious osteomyelitis

Various conditions, including bacterial infection, can promote osteonecrosis. For example, following invasive dental therapy with anti-bone resorptive agents, some patients develop osteonecrosis in the jaw; however, pathological mechanisms underlying these outcomes remain unknown. Here, we show that...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morita, Mayu, Iwasaki, Ryotaro, Sato, Yuiko, Kobayashi, Tami, Watanabe, Ryuichi, Oike, Takatsugu, Nakamura, Satoshi, Keneko, Yosuke, Miyamoto, Kana, Ishihara, Kazuyuki, Iwakura, Yoichiro, Ishii, Ken, Matsumoto, Morio, Nakamura, Masaya, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384218/
https://ncbi.nlm.nih.gov/pubmed/28387378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46322
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