Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Anti-bone resorptive drugs such as bisphosphonates, the anti-RANKL antibody (denosumab), or selective estrogen receptor modulators (SERMs) have been developed to treat osteoporosis. Mechanisms underlying activity of bisphosphonates or denosumab in this context are understood, while it is less clear...

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Publicado en:PLoS One
Autores principales: Morita, Mayu, Sato, Yuiko, Iwasaki, Ryotaro, Kobayashi, Tami, Watanabe, Ryuichi, Oike, Takatsugu, Miyamoto, Kana, Toyama, Yoshiaki, Matsumoto, Morio, Nakamura, Masaya, Kawana, Hiromasa, Nakagawa, Taneaki, Miyamoto, Takeshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089792/
https://ncbi.nlm.nih.gov/pubmed/27802325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165922
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