Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections

[Image: see text] Gram-negative uropathogenic Escherichia coli (UPEC) bacteria are a causative pathogen of urinary tract infections (UTIs). Previously developed antivirulence inhibitors of the type 1 pilus adhesin, FimH, demonstrated oral activity in animal models of UTI but were found to have limit...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Med Chem
Главные авторы: Mydock-McGrane, Laurel, Cusumano, Zachary, Han, Zhenfu, Binkley, Jana, Kostakioti, Maria, Hannan, Thomas, Pinkner, Jerome S., Klein, Roger, Kalas, Vasilios, Crowley, Jan, Rath, Nigam P., Hultgren, Scott J., Janetka, James W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2016
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087331/
https://ncbi.nlm.nih.gov/pubmed/27689912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00948
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы