Chemotherapy and Stem Cell Transplantation Increase p16(INK4a) Expression, a Biomarker of T-cell Aging

The expression of markers of cellular senescence increases exponentially in multiple tissues with aging. Age-related physiological changes may contribute to adverse outcomes in cancer survivors. To investigate the impact of high dose chemotherapy and stem cell transplantation on senescence markers i...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Wood, William A., Krishnamurthy, Janakiraman, Mitin, Natalia, Torrice, Chad, Parker, Joel S., Snavely, Anna C., Shea, Thomas C., Serody, Jonathan S., Sharpless, Norman E.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049997/
https://ncbi.nlm.nih.gov/pubmed/27591832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.029
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