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Expression of p16(INK4a) as a biomarker of T-cell aging in HIV-infected patients prior to and during antiretroviral therapy

The p16(INK4a) tumor suppressor gene is a mediator of cellular senescence and has been suggested to be a biomarker of ‘molecular’ age in several tissues including T-cells. To determine the association of both active and suppressed HIV infection with T-cell aging, T-cell p16(INK4a) expression was com...

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Bibliografiska uppgifter
Huvudupphovsmän: Nelson, Julie A. E., Krishnamurthy, Janakiraman, Menezes, Prema, Liu, Yan, Hudgens, Michael G., Sharpless, Norman E., Eron, Joseph J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697001/
https://ncbi.nlm.nih.gov/pubmed/22738669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00856.x
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