Chemotherapy and Stem Cell Transplantation Increase p16(INK4a) Expression, a Biomarker of T-cell Aging

The expression of markers of cellular senescence increases exponentially in multiple tissues with aging. Age-related physiological changes may contribute to adverse outcomes in cancer survivors. To investigate the impact of high dose chemotherapy and stem cell transplantation on senescence markers i...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wood, William A., Krishnamurthy, Janakiraman, Mitin, Natalia, Torrice, Chad, Parker, Joel S., Snavely, Anna C., Shea, Thomas C., Serody, Jonathan S., Sharpless, Norman E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049997/
https://ncbi.nlm.nih.gov/pubmed/27591832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.029
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