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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging
Expression of the p16(INK4a) tumor suppressor sharply increases with age in most mammalian tissues, and contributes to an age-induced functional decline of certain self-renewing compartments. These observations have suggested that p16(INK4a) expression could be a biomarker of mammalian aging. To tra...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752333/ https://ncbi.nlm.nih.gov/pubmed/19485966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00489.x |
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