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A quantitative model for age-dependent expression of the p16INK4a tumor suppressor
Recent work has shown that expression of the p16(INK4a) tumor suppressor increases with chronological age. Expression is accelerated by gerontogenic behaviors such as tobacco use and physical inactivity, and is also influenced by allelic genotype of a polymorphic single nucleotide polymorphism (SNP)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757807/ https://ncbi.nlm.nih.gov/pubmed/19805338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904405106 |
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