Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer

As a master regulator of chromatin function, the lysine methyltransferase EZH2 orchestrates transcriptional silencing of developmental gene networks. Overexpression of EZH2 is commonly observed in human epithelial cancers, such as non-small cell lung carcinoma (NSCLC), yet definitive demonstration o...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Discov
Main Authors: Zhang, Haikuo, Qi, Jun, Reyes, Jaime M., Li, Lewyn, Rao, Prakash K., Li, Fugen, Lin, Charles Y., Perry, Jennifer A., Lawlor, Matthew A., Federation, Alexander, De Raedt, Thomas, Li, Yvonne Y., Liu, Yan, Duarte, Melissa A., Zhang, Yanxi, Herter-Sprie, Grit S., Kikuchi, Eiki, Carretero, Julian, Perou, Charles M., Reibel, Jacob B., Paulk, Joshiawa, Bronson, Roderick T., Watanabe, Hideo, Fillmore, Christine M., Kim, Carla F., Hammerman, Peter S., Brown, Myles, Cichowski, Karen, Long, Henry, Bradner, James E., Wong, Kwok-Kin
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010480/
https://ncbi.nlm.nih.gov/pubmed/27312177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0164
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker