Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer

As a master regulator of chromatin function, the lysine methyltransferase EZH2 orchestrates transcriptional silencing of developmental gene networks. Overexpression of EZH2 is commonly observed in human epithelial cancers, such as non-small cell lung carcinoma (NSCLC), yet definitive demonstration o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Zhang, Haikuo, Qi, Jun, Reyes, Jaime M., Li, Lewyn, Rao, Prakash K., Li, Fugen, Lin, Charles Y., Perry, Jennifer A., Lawlor, Matthew A., Federation, Alexander, De Raedt, Thomas, Li, Yvonne Y., Liu, Yan, Duarte, Melissa A., Zhang, Yanxi, Herter-Sprie, Grit S., Kikuchi, Eiki, Carretero, Julian, Perou, Charles M., Reibel, Jacob B., Paulk, Joshiawa, Bronson, Roderick T., Watanabe, Hideo, Fillmore, Christine M., Kim, Carla F., Hammerman, Peter S., Brown, Myles, Cichowski, Karen, Long, Henry, Bradner, James E., Wong, Kwok-Kin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010480/
https://ncbi.nlm.nih.gov/pubmed/27312177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0164
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados