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Autophagy sustains pancreatic cancer growth through both cell autonomous and non-autonomous mechanisms
Autophagy has been shown to be elevated in pancreatic adenocarcinoma (PDAC) and its role in promoting established tumor growth has made it a promising therapeutic target. However, due to limitations of prior mouse models as well as the lack of potent and selective autophagy inhibitors, the ability t...
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| 發表在: | Cancer Discov |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835190/ https://ncbi.nlm.nih.gov/pubmed/29317452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0952 |
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