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Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
The activities and genome-wide specificities of CRISPR-Cas Cpf1 nucleases(1) are not well defined. We show that two Cpf1 nucleases from Acidaminococcus sp. BV3L6 and Lachnospiraceae bacterium ND2006 (AsCpf1 and LbCpf1, respectively) have on-target efficiencies in human cells comparable with those of...
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| Publicado en: | Nat Biotechnol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980201/ https://ncbi.nlm.nih.gov/pubmed/27347757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3620 |
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