Cargando...
Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq
Circularization for in vitro reporting of cleavage effects by sequencing (CIRCLE-seq) is a sensitive and unbiased method for defining the genome-wide activity (on-target and off-target) of CRISPR-Cas9 nucleases by selective sequencing of nuclease-cleaved genomic DNA. Here we describe a detailed expe...
Guardado en:
| Publicado en: | Nat Protoc |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512799/ https://ncbi.nlm.nih.gov/pubmed/30341435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0055-0 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|