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GENOME EDITING IN HUMAN CELLS USING CRISPR/CAS NUCLEASES

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system has been broadly adopted for highly efficient genome editing in a variety of model organisms and human cell types. Unlike previous genome editing technologies such as Zinc Finger Nucleases (ZFNs) and...

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Detalhes bibliográficos
Publicado no:Curr Protoc Mol Biol
Main Authors: Wyvekens, Nicolas, Tsai, Shengdar, Joung, J. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852847/
https://ncbi.nlm.nih.gov/pubmed/26423589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142727.mb3103s112
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