A carregar...
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
Monomeric CRISPR-Cas9 nucleases are widely used for targeted genome editing but can induce unwanted off-target mutations with high frequencies. Here we describe dimeric RNA-guided FokI Nucleases (RFNs) that recognize extended sequences and can edit endogenous genes with high efficiencies in human ce...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090141/ https://ncbi.nlm.nih.gov/pubmed/24770325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2908 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|