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FLASH Assembly of TALENs Enables High-Throughput Genome Editing

Engineered transcription activator-like effector nucleases (TALENs) have shown promise as facile and broadly applicable genome editing tools. However, no publicly available high-throughput method for constructing TALENs has been published and large-scale assessments of the success rate and targeting...

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Hlavní autoři: Reyon, Deepak, Tsai, Shengdar Q., Khayter, Cyd, Foden, Jennifer A., Sander, Jeffry D., Joung, J. Keith
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558947/
https://ncbi.nlm.nih.gov/pubmed/22484455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2170
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