Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

BACKGROUND: Genome-wide association studies have identified BIN1 within the second most significant susceptibility locus in late-onset Alzheimer’s disease (AD). BIN1 undergoes complex alternative splicing to generate multiple isoforms with diverse functions in multiple cellular processes including e...

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Библиографические подробности
Опубликовано в: :Mol Neurodegener
Главные авторы: De Rossi, Pierre, Buggia-Prévot, Virginie, Clayton, Benjamin L. L., Vasquez, Jared B., van Sanford, Carson, Andrew, Robert J., Lesnick, Ruben, Botté, Alexandra, Deyts, Carole, Salem, Someya, Rao, Eshaan, Rice, Richard C., Parent, Angèle, Kar, Satyabrata, Popko, Brian, Pytel, Peter, Estus, Steven, Thinakaran, Gopal
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973113/
https://ncbi.nlm.nih.gov/pubmed/27488240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0124-1
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