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Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons
Neurons have developed elaborate mechanisms for sorting of proteins to their destination in dendrites and axons as well as dynamic local trafficking. Recent evidence suggests that polarized axonal sorting of β-site converting enzyme 1 (BACE1), a type I transmembrane aspartyl protease involved in Alz...
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| Publicado no: | Bioessays |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512854/ https://ncbi.nlm.nih.gov/pubmed/26126792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500019 |
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