BIN1 localization is distinct from Tau tangles in Alzheimer’s disease

BIN1 is the second most significant Alzheimer’s disease (AD) risk factor gene identified through genome-wide association studies. BIN1 is an adaptor protein that can bind to several proteins including c-Myc, clathrin, adaptor protein-2 and dynamin. BIN1 is widely expressed in the brain and periphera...

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Pubblicato in:Matters (Zur)
Autori principali: De Rossi, Pierre, Buggia-Prevot, Virginie, Andrew, Robert J, Krause, Sofia V, Woo, Elizabeth, Nelson, Peter T, Pytel, Peter, Thinakaran, Gopal
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823513/
https://ncbi.nlm.nih.gov/pubmed/29479533
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