Aberrant accrual of BIN1 near Alzheimer’s disease amyloid deposits in transgenic models

Bridging integrator 1 (BIN1) is the most significant late‐onset Alzheimer’s disease (AD) susceptibility locus identified via genome‐wide association studies. BIN1 is an adaptor protein that regulates membrane dynamics in the context of endocytosis and membrane remodeling. An increase in BIN1 express...

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Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: De Rossi, Pierre, Andrew, Robert J., Musial, Timothy F., Buggia‐Prevot, Virginie, Xu, Guilian, Ponnusamy, Moorthi, Ly, Han, Krause, Sofia V., Rice, Richard C., de l’Estoile, Valentine, Valin, Tess, Salem, Someya, Despa, Florin, Borchelt, David R., Bindokas, Vytas P., Nicholson, Daniel A., Thinakaran, Gopal
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542723/
https://ncbi.nlm.nih.gov/pubmed/30506549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12687
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