Aberrant accrual of BIN1 near Alzheimer’s disease amyloid deposits in transgenic models

Bridging integrator 1 (BIN1) is the most significant late‐onset Alzheimer’s disease (AD) susceptibility locus identified via genome‐wide association studies. BIN1 is an adaptor protein that regulates membrane dynamics in the context of endocytosis and membrane remodeling. An increase in BIN1 express...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: De Rossi, Pierre, Andrew, Robert J., Musial, Timothy F., Buggia‐Prevot, Virginie, Xu, Guilian, Ponnusamy, Moorthi, Ly, Han, Krause, Sofia V., Rice, Richard C., de l’Estoile, Valentine, Valin, Tess, Salem, Someya, Despa, Florin, Borchelt, David R., Bindokas, Vytas P., Nicholson, Daniel A., Thinakaran, Gopal
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542723/
https://ncbi.nlm.nih.gov/pubmed/30506549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12687
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