Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

BACKGROUND: Genome-wide association studies have identified BIN1 within the second most significant susceptibility locus in late-onset Alzheimer’s disease (AD). BIN1 undergoes complex alternative splicing to generate multiple isoforms with diverse functions in multiple cellular processes including e...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: De Rossi, Pierre, Buggia-Prévot, Virginie, Clayton, Benjamin L. L., Vasquez, Jared B., van Sanford, Carson, Andrew, Robert J., Lesnick, Ruben, Botté, Alexandra, Deyts, Carole, Salem, Someya, Rao, Eshaan, Rice, Richard C., Parent, Angèle, Kar, Satyabrata, Popko, Brian, Pytel, Peter, Estus, Steven, Thinakaran, Gopal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973113/
https://ncbi.nlm.nih.gov/pubmed/27488240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0124-1
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