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Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

BACKGROUND: Genome-wide association studies have identified BIN1 within the second most significant susceptibility locus in late-onset Alzheimer’s disease (AD). BIN1 undergoes complex alternative splicing to generate multiple isoforms with diverse functions in multiple cellular processes including e...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Neurodegener
Päätekijät: De Rossi, Pierre, Buggia-Prévot, Virginie, Clayton, Benjamin L. L., Vasquez, Jared B., van Sanford, Carson, Andrew, Robert J., Lesnick, Ruben, Botté, Alexandra, Deyts, Carole, Salem, Someya, Rao, Eshaan, Rice, Richard C., Parent, Angèle, Kar, Satyabrata, Popko, Brian, Pytel, Peter, Estus, Steven, Thinakaran, Gopal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973113/
https://ncbi.nlm.nih.gov/pubmed/27488240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0124-1
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