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APP receptor? To be or not to be…
Amyloid Precursor Protein (APP) and its metabolites play a critical role in Alzheimer’s disease pathogenesis. The idea that APP may function as a receptor has gained momentum based on its structural similarities to type I transmembrane receptors, and the identification of putative APP ligands. Here...
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Publicado no: | Trends Pharmacol Sci |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846520/ https://ncbi.nlm.nih.gov/pubmed/26837733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.01.005 |
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