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APP receptor? To be or not to be…

Amyloid Precursor Protein (APP) and its metabolites play a critical role in Alzheimer’s disease pathogenesis. The idea that APP may function as a receptor has gained momentum based on its structural similarities to type I transmembrane receptors, and the identification of putative APP ligands. Here...

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Bibliografische gegevens
Gepubliceerd in:Trends Pharmacol Sci
Hoofdauteurs: Deyts, Carole, Thinakaran, Gopal, Parent, Angèle T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846520/
https://ncbi.nlm.nih.gov/pubmed/26837733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.01.005
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