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APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

Amyloid precursor protein (APP) and its metabolites play key roles in Alzheimer’s disease (AD) pathophysiology. Whereas short amyloid-β (Aβ) peptides derived from APP are pathogenic, the APP holoprotein serves multiple purposes in the nervous system through its cell adhesion and receptor-like proper...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Rep
मुख्य लेखकों: Deyts, Carole, Clutter, Mary, Pierce, Nicholas, Chakrabarty, Paramita, Ladd, Thomas B., Goddi, Anna, Rosario, Awilda M., Cruz, Pedro, Vetrivel, Kulandaivelu, Wagner, Steven L., Thinakaran, Gopal, Golde, Todd E., Parent, Angèle T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508668/
https://ncbi.nlm.nih.gov/pubmed/31042463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.087
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