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APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

Amyloid precursor protein (APP) and its metabolites play key roles in Alzheimer’s disease (AD) pathophysiology. Whereas short amyloid-β (Aβ) peptides derived from APP are pathogenic, the APP holoprotein serves multiple purposes in the nervous system through its cell adhesion and receptor-like proper...

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מידע ביבליוגרפי
הוצא לאור ב:	Cell Rep
Main Authors:	Deyts, Carole, Clutter, Mary, Pierce, Nicholas, Chakrabarty, Paramita, Ladd, Thomas B., Goddi, Anna, Rosario, Awilda M., Cruz, Pedro, Vetrivel, Kulandaivelu, Wagner, Steven L., Thinakaran, Gopal, Golde, Todd E., Parent, Angèle T.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2019
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6508668/ https://ncbi.nlm.nih.gov/pubmed/31042463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.087
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APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

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