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APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model
Amyloid precursor protein (APP) and its metabolites play key roles in Alzheimer’s disease (AD) pathophysiology. Whereas short amyloid-β (Aβ) peptides derived from APP are pathogenic, the APP holoprotein serves multiple purposes in the nervous system through its cell adhesion and receptor-like proper...
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| 發表在: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508668/ https://ncbi.nlm.nih.gov/pubmed/31042463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.087 |
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