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Mechanisms of Disease: new therapeutic strategies for Alzheimer’s disease—targeting amyloid precursor protein processing in lipid rafts

Alzheimer’s disease (AD) is the most common cause of age-related dementia. Pathologically, AD is characterized by the deposition in the brain of amyloid-β peptides derived from proteolysis of amyloid precursor protein (APP) by β-site APP cleaving enzyme 1 (BACE1) andγ-secretase. Growing evidence imp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cheng, Haipeng, Vetrivel, Kulandaivelu S., Gong, Ping, Parent, Angèle, Thinakaran, Gopal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880530/
https://ncbi.nlm.nih.gov/pubmed/17611486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncpneuro0549
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