Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

BACKGROUND: Genome-wide association studies have identified BIN1 within the second most significant susceptibility locus in late-onset Alzheimer’s disease (AD). BIN1 undergoes complex alternative splicing to generate multiple isoforms with diverse functions in multiple cellular processes including e...

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發表在:Mol Neurodegener
Main Authors: De Rossi, Pierre, Buggia-Prévot, Virginie, Clayton, Benjamin L. L., Vasquez, Jared B., van Sanford, Carson, Andrew, Robert J., Lesnick, Ruben, Botté, Alexandra, Deyts, Carole, Salem, Someya, Rao, Eshaan, Rice, Richard C., Parent, Angèle, Kar, Satyabrata, Popko, Brian, Pytel, Peter, Estus, Steven, Thinakaran, Gopal
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973113/
https://ncbi.nlm.nih.gov/pubmed/27488240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0124-1
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