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Role of Plasmodium vivax Dihydropteroate Synthase Polymorphisms in Sulfa Drug Resistance
Dihydropteroate synthase (DHPS) is a known sulfa drug target in malaria treatment, existing as a bifunctional enzyme together with hydroxymethyldihydropterin pyrophosphokinase (HPPK). Polymorphisms in key residues of Plasmodium falciparum DHPS (PfDHPS) have been characterized and linked to sulfa dru...
Enregistré dans:
| Publié dans: | Antimicrob Agents Chemother |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958149/ https://ncbi.nlm.nih.gov/pubmed/27161627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01835-15 |
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