Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization

BACKGROUND: Serine hydroxymethyltransferase (SHMT), a pyridoxal phosphate-dependent enzyme, plays a vital role in the de novo pyrimidine biosynthesis pathway in malaria parasites. Two genes have been identified in Plasmodium spp. encoding a cytosolic SHMT (cSHMT) and putative mitochondria SHMT (mSHM...

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Hlavní autoři: Pornthanakasem, Wichai, Kongkasuriyachai, Darin, Uthaipibull, Chairat, Yuthavong, Yongyuth, Leartsakulpanich, Ubolsree
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521198/
https://ncbi.nlm.nih.gov/pubmed/23173711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-387
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