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The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation

The herpes simplex virus (HSV) virion host shutoff (vhs) RNase destabilizes cellular and viral mRNAs, suppresses host protein synthesis, dampens antiviral responses, and stimulates translation of viral mRNAs. vhs mutants display a host range phenotype: translation of viral true late mRNAs is severel...

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書目詳細資料
發表在:J Virol
Main Authors: Dauber, Bianca, Poon, David, dos Santos, Theodore, Duguay, Brett A., Mehta, Ninad, Saffran, Holly A., Smiley, James R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907241/
https://ncbi.nlm.nih.gov/pubmed/27099317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03180-15
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