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Evidence for Translational Regulation by the Herpes Simplex Virus Virion Host Shutoff Protein

The herpes simplex virus (HSV) virion host shutoff protein (vhs) encoded by gene UL41 is an mRNA-specific RNase that triggers accelerated degradation of host and viral mRNAs in infected cells. We report here that vhs is also able to modulate reporter gene expression without greatly altering the leve...

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Autores principales: Saffran, Holly A., Read, G. Sullivan, Smiley, James R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876651/
https://ncbi.nlm.nih.gov/pubmed/20357089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01819-09
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