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Evidence for Translational Regulation by the Herpes Simplex Virus Virion Host Shutoff Protein

The herpes simplex virus (HSV) virion host shutoff protein (vhs) encoded by gene UL41 is an mRNA-specific RNase that triggers accelerated degradation of host and viral mRNAs in infected cells. We report here that vhs is also able to modulate reporter gene expression without greatly altering the leve...

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Détails bibliographiques
Auteurs principaux: Saffran, Holly A., Read, G. Sullivan, Smiley, James R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876651/
https://ncbi.nlm.nih.gov/pubmed/20357089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01819-09
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